Nuances in Prescribing Antidepressants

In this episode, Margaret and Preston present how two psychiatrists think about prescribing medications for depression. Using different common clinical scenarios, they discuss standard clinical guidelines, navigating weight gain and loss with SSRIs, augmentation of SSRI’s, and sexual side effects. 

See notes below for recommendations in the episode. 
VA/DoD MDD treatment guidelines, 2022
⁠https://www.healthquality.va.gov/guidelines/MH/mdd/⁠

American College of Physicians Depression 
⁠https://www.acpjournals.org/doi/10.7326/M22-2056⁠

Weight Change and Antidepressants
⁠https://pubmed.ncbi.nlm.nih.gov/33022115/⁠

Pregnancy/Perinatal/Breastfeeding
⁠https://womensmentalhealth.org/specialty-clinics/psychiatric-disorders-during-pregnancy/⁠

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Produced by Dr Glaucomflecken & Human Content
Get in Touch: ⁠⁠⁠⁠⁠⁠⁠⁠⁠howtobepatientpod.com⁠⁠

Chapters:
00:00 Vraylar Ad Rant
00:38 Show Intro And Topic
02:04 Figs Campaign Story
05:01 Life Updates And Summer
08:33 Prescribing Nuance And Evidence
15:53 Vignette Switch Or Augment
23:01 Cross Taper And Auvelity Talk
28:05 NMDA Antidepressant Basics
29:28 New Meds Quick Hits
31:24 Evidence and Pharma Skepticism
33:31 MAOIs and TCAs Tradeoffs
35:30 TCA Overdose and Safety
38:23 Weight Gain and GLP-1 Future
52:23 Wrap Up and Credits

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